“Jesus Himself was in the stern, asleep on the cushion; and they woke Him and said to Him, ‘Teacher, do You not care that we are perishing?'”  (Mark 4:38)

The verse previous (:37) indicates that a “fierce gale of wind” had arisen and the boat that Jesus and His disciples were in was filling up with water, and appeared about to sink. It is in that context that :38 indicates that His disciples awoke Him and asked the question: “Do You not care that we are perishing?”
Unfortunately that may be typical of our responses to the Lord in times of difficulty. We are often quick to ask, “Don’t You care?”; so ready to accuse Him of not being concerned about us. 

In one sense that is somewhat understandable, since our circumstances can be difficult, and we don’t comprehend what is happening to us and why. We can’t fathom His plan and perspective, and our wisdom is limited. We just wonder why He doesn’t heal, or provide, or blast all our enemies, or whatever the need of the occasion is.

But in another sense that response is very myopic and faithless. What cause do we have to think that God doesn’t care? He has been so diligent in providing our universe with intricate detail so that our every need for oxygen, food, etc. are met through His creation. He has given us His word because He cared to communicate with us; and most significantly He gave His own Son, Jesus, to die for our sins — solely on the basis of His love for an undeserving world.

In light of this, it indeed quite short-sighted then, at the first sign of difficulty, for us to raise our heads to heaven and shout: “Do You not care?” Is there some plan I don’t understand? Very possible. Do I lack His perspective on events? Absolutely. Is this painful now but will be worth it later? We have seen that happen often. But “Do You not care?” We need to re-think asking that question. There is really no basis, in history or in His character, for asking that.